<a href="https://www.freepik.com/free-ai-image/human-blood-globulins_97747193.htm#fromView=search&amp;page=1&amp;position=9&amp;uuid=0a1d6c78-ecf9-4134-a9b7-52c8d3847ea2">Image by frimufilms on Freepik</a>Anaemia is when haemoglobin (Hb) concentration and red blood cell (RBC) numbers are lower than expected and insufficient to meet the amount you need to function effectively. This means that the RBCs will not be able to carry enough oxygen.&nbsp;<ul><li>Anaemia affects roughly one-third of the world’s population, with more than 60% of them in Africa</li><li>It’s often a sign of nutritional deficiency and ill health</li><li>Anaemia is also associated with death and disease in women and children.</li></ul><h2 style="margin-left:0cm;">Anaemia symptoms</h2>Anaemia is subtle at the earliest. The body tries to compensate for the inadequacy initially, but symptoms may appear as the anaemia continues or worsens. The symptoms may include:<ul><li>Pale skin (pallor)</li><li>Cold hands and feet</li><li>Tiredness or weakness</li><li>Dizziness, lightheadedness, or feeling like you are about to pass out</li><li>Fast or unusual heartbeat</li><li>Shortness of breath</li><li>Headache&nbsp;</li><li>Pain</li><li>Poor growth&nbsp;</li></ul>The severity of the symptoms depends on the level of anaemia, the persistence of the cause, and how well the body compensates for the inadequacy.&nbsp;<h2 style="margin-left:0cm;">What are the causes of anaemia in Africa</h2>Anaemia occurs either because:<ol><li>the body does not produce enough blood or</li><li>an excess number of red cells are destroyed, or</li><li>the body is losing blood at a faster rate than it produces</li></ol>These three mechanisms result from many causes. The common causes of anaemia in Nigeria include&nbsp;<ul><li>genetic conditions (e.g., thalassemia in parts of the Mediterranean, sickle cell in Africa)</li><li>nutritional deficiencies other than iron deficiency (i.e., folic acid, vitamins A and B-12)</li><li>factors related to reproduction (e.g., high fertility, obstetric complications, contraceptives)</li><li>infections (e.g., HIV/AIDS, tuberculosis, diarrhoea) that increase requirements for iron and other micronutrients</li><li>parasitic infections such as malaria and worm infestation</li></ul>Malaria is a leading cause of anaemia in Sub-Saharan Africa, as is iron deficiency.<h2 style="margin-left:0cm;">Risk factors</h2>The following factors place you at increased risk of anaemia, they include:<ul><li>Nutritional deficiency: low intake of minerals and vitamins, such as iron, copper, vitamin B-12, and folate&nbsp;</li><li>Intestinal disorders: intestinal disorders such as Crohn’s disease and celiac disease affect the absorption of nutrients in your small intestine and increase your risk of developing anaemia</li><li>Menstrual disorders: excess blood loss during menstruation is a risk factor</li><li>Pregnancy: Increased energy and nutrient demands and fluid retention during pregnancy can lead to anaemia</li><li>Chronic conditions: Chronic conditions like cancer or longstanding infections deplete your iron stores, while kidney failure can affect the release of the hormone that controls blood production.&nbsp;</li></ul>Chronic blood loss from an ulcer or other sources within the body can deplete the body's store of iron, leading to iron deficiency anaemia.<ul><li>Family history:&nbsp;inherited conditions, such as sickle cell anaemia, make you vulnerable to becoming anaemic due to increased destruction of red cells</li><li>Old age: People over age 65 are at increased risk of anaemia</li></ul>Other factors include blood diseases like haemophilia, autoimmune disorders, alcoholism, exposure to toxic chemicals like camphor, and the use of some medications can affect red blood cell production and lead to anaemia.<h2 style="margin-left:0cm;">Diagnosis</h2><figure class="image"><img src="https://tenbadgers-myhealthvoice.s3.eu-central-1.amazonaws.com/image_48e230bd77_d369ff77c3.webp"></figure><a href="https://www.freepik.com/free-photo/coronavirus-blood-samples-arrangement-lab_18684532.htm#fromView=search&amp;page=1&amp;position=18&amp;uuid=dd6f9a27-a349-4831-a0aa-e91ec4f1f230">Image by freepik</a>Diagnosis of anaemia is a combination of clinical presentation and laboratoryLaboratory tests for anaemia generally include the following:<ul><li>Packed cell volume (PCV) estimation: involves spinning your blood in a tube to see how much of it is red blood cells</li><li>Complete blood count (CBC): also called full blood count, this test estimates the levels of individual components of your blood, including white blood cells, red blood cells, platelets, reticulocytes, haemoglobin, differential cells, etc.</li><li>Peripheral blood smear: involves using a microscope to examine your blood for its colour, shape, size</li><li>Haemoglobin estimation</li><li>Serum iron estimation</li><li>Serum bilirubin</li><li>Haemoglobin electrophoresis</li><li>Reticulocyte count</li><li>Urinalysis</li><li>Liver function tests</li><li>Renal function test</li><li>Bone marrow biopsy</li></ul><h2 style="margin-left:0cm;">Treatment</h2>Treatment for anaemia depends on the cause or type of anaemia. Treatments for common forms of anaemia include:<ul><li>Iron-deficiency anaemia: iron supplements and dietary changes.</li><li>Vitamin deficiency anaemia: vitamins and dietary supplements.</li><li style="text-align:justify;">Thalassemia: folic acid supplements, iron chelation, and, for some people, blood transfusions and bone marrow transplants.</li><li>Anaemia of chronic disease: treatment of underlying disease.</li><li>Aplastic anaemia: blood transfusion or bone marrow transplant.</li><li>Sickle cell anaemia: oxygen therapy, pain relief medication, and intravenous fluids: antibiotics, folic acid supplements, blood transfusions, and hydroxyurea may be added.</li><li style="text-align:justify;">Haemolytic anaemia: treatment of the underlying cause</li></ul><h2 style="margin-left:0cm;">Prevention</h2>Prevention can be&nbsp;achieved by enforcing individual/family and government policies.On individual levelIron deficiency and vitamin-deficiency anaemia can be prevented by consuming the right diet. Suchnutrient can be gotten from the following sources:<ul><li>Iron:&nbsp;from red meat, dark-green leafy vegetables, beans and lentils, dried-fruits and iron-fortified cereals.</li><li>Folate/folic acid:&nbsp;from dark-green leafy vegetables, whole fruits or fruit juices, kidney beans, green peas, peanuts and fortified products such as bread, cereal, pasta, and rice.</li><li>Vitamin B-12:&nbsp;sources include dairy products, meat, soy products and fortified cereal.</li><li style="text-align:justify;">Vitamin C: citrus fruits – whole or juiced, strawberries, peppers, broccoli, melons and tomatoes.</li></ul>On Governmental levelThe three major causes of anaemia (iron deficiency, malaria and helminth infections) can be addressed during contacts with vulnerable groups using a combination of key interventions, as needed.Five Key Interventions<ul><li>Iron supplements targeted to at-risk groups</li><li>Fortification of staple foods with iron and other micronutrients that cause anaemia for the general population&nbsp;</li><li>Supply of iron-fortified foods targeted to at-risk groups</li><li>Prevent and treat malaria</li><li>Use of insecticide-treated materials and bed nets to prevent anaemia</li><li>Deworming (anthelmintics) in at-risk groups</li></ul>Other important interventions to decrease anaemia:<ul><li>Expand immunization coverage</li><li>Prevent and manage obstetric complications, particularly excessive bleeding</li><li>Promote birth spacing through use of modern contraceptives and exclusive breastfeeding</li><li>Promote use of contraceptives that decrease blood loss</li><li>Improve water and sanitation facilities/practices</li></ul><h2 style="margin-left:0cm;">Conclusion</h2>Anaemia is a huge problem in Africa, but it is manageable with interventions at the individual and government levels. The primary cause of anaemia in the continent include iron deficiency, malaria, and complications of pregnancy and delivery. These causes are controllable.&nbsp;

The Prevalence of Anaemia in Africa

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<a href="https://www.pexels.com/photo/medical-eyeglasses-and-full-of-blood-vials-on-diaper-4230620/">Photo by Karolina Grabowska from Pexels</a>Human blood belongs to one of four main blood groups: A, AB, B, and O. Each of these groups can also be positive or negative for the Rhesus factor, which means you can have an A positive or an A negative blood, just as you can have for AB,&nbsp; B, and O blood groups. But what does this grouping mean to you, and why should you care?<h2 style="margin-left:0cm;text-align:justify;">Blood antigens and antibodies</h2>Blood grouping is based on the presence or absence of antigens and antibodies in your blood. Antigens are proteins found on the red cell surface, while antibodies are natural proteins in plasma.&nbsp;An antigen triggers your immune system to generate antibodies. The antibodies alert your body to destroy the antigens they recognise as foreign.&nbsp;Red blood cells have different types of antigens used to group them. The most commonly recognised blood groups are:<ul><li style="text-align:justify;">The ABO blood grouping system&nbsp;</li><li style="text-align:justify;">The Rhesus (Rh) blood grouping system</li></ul><h3 style="margin-left:0cm;text-align:justify;">ABO system</h3>In the ABO system, the blood group is based on the presence or absence of the A and B antigens. There are four blood groups in this grouping system.<ul><li style="text-align:justify;">Group A&nbsp;- has A antigen and anti-B antibody</li><li style="text-align:justify;">Group B - has B antigen and anti-A antibody</li><li style="text-align:justify;">Group AB - has both A and B antigens but no antibodies</li><li style="text-align:justify;">Group O - has no antigens but has both anti-A and anti-B antibodies</li></ul>Group O blood is the most common blood group in Nigeria. More than half of Nigerians (53%) have group O blood. Very few (less than 4%) have group AB blood.&nbsp;According to the ABO grouping system, your body tolerates the antigens in your blood and produces antibodies against the antigens you do not have.<h3 style="margin-left:0cm;text-align:justify;">ABO blood compatibility&nbsp;</h3>The ABO blood grouping determines who you can donate blood to or receive blood from. This is known as blood compatibility or the capacity of blood from two individuals to combine without destroying each other.Blood transfusion can safely be done only between two compatible blood groups. This means you must only receive blood your body will not react to.&nbsp;For example, if you have blood group A, your safest option is to receive blood group A. If you receive blood from an incompatible blood group, say group B, your anti-B antibodies will attack the B antigens on the donor red cells, which could be life-threatening.A safer option will be to receive group O blood. Because the group O blood has no antigen, it can safely be given to people with any other blood group.The ABO blood grouping compatibility is summarised as follows:<ul><li style="text-align:justify;">Group A: individuals with this blood group can donate to individuals with group A or AB blood but can receive blood only from individuals with group A or O blood.</li><li style="text-align:justify;">Group B: individuals with this blood group can donate to individuals with group B or AB blood but can receive blood only from individuals with group B or group O blood.</li><li style="text-align:justify;">Group AB: individuals with this blood group can donate only to individuals with group AB blood but can receive blood from any other blood group.</li><li style="text-align:justify;">Group O: individuals with this blood group can donate to individuals with any blood group but can receive blood only from individuals with group O blood..&nbsp;</li></ul><h3 style="margin-left:0cm;text-align:justify;">Rh system</h3>In the Rh blood grouping system, the blood group is classified depending on the presence of the Rhesus (Rh) factor. The Rh factor is coded for by the D antigen. So if your blood has the Rhesus factor, you are Rhesus-D positive (RhD-positive). If it does not, you are Rhesus-D negative (RhD-negative).The ABO and Rhesus grouping systems are often taken together to give your blood type. That means your blood group can be one of the following:<ul><li style="text-align:justify;">O-negative (O-)</li><li style="text-align:justify;">O-positive (O+)</li><li style="text-align:justify;">A-negative (A-)</li><li style="text-align:justify;">A-positive (A+)</li><li style="text-align:justify;">B-negative (B-)</li><li style="text-align:justify;">B-positive (B+)</li><li style="text-align:justify;">AB-positive (AB+)</li><li style="text-align:justify;">AB-negative (AB-)</li></ul>Individuals with AB-positive blood are considered universal recipients because they can receive blood from any other blood group, while a person with type O-negative blood is considered a universal donor because their blood can be safely given to anyone.&nbsp;<h3 style="margin-left:0cm;text-align:justify;">Rhesus compatibility&nbsp;</h3>Rhesus compatibility is not often considered in blood group grouping and crossmatching for blood transfusion, but the compatibility between a pregnant woman and the foetus is is very important.&nbsp;A child can inherit the Rhesus-D antigen from either the mother or father. If the mother is RhD-negative but the child is RhD-positive due to inheritance of Rhesus-D antigen from the father, there will be Rhesus incompatibility between the mother and child.&nbsp;The mother may produce anti-D antibodies that react with the child’s RhD antigens, causing severe complications for the child. This is preventable. Speak with your obstetrician or gynaecologist to discuss the preventions if you are a RhD-negative mother.<h3 style="margin-left:0cm;text-align:justify;">How to check your blood group</h3><figure class="image"><img src="https://tenbadgers-myhealthvoice.s3.eu-central-1.amazonaws.com/image_888d964667_2b79e8c23b.webp"></figure><a href="https://commons.wikimedia.org/wiki/File:Ics-codablock-blood-bag_sample.jpg">ICSident at German Wikipedia</a>,&nbsp;<a href="https://creativecommons.org/licenses/by-sa/3.0">CC BY-SA 3.0</a>, via Wikimedia CommonsYou can check your blood group by visiting a registered laboratory. A laboratory scientist will collect your blood and test it for the blood group antigens that we've outlined.&nbsp;The scientist will tie a tourniquet around your wrist or arm and insert a syringe into a vein to collect your blood into a sample bottle or syringe.Your red blood cells will then be mixed with reagents containing antibodies against the common red cell antigens. That is, anti-A and anti-B antibodies—a third reagent containing anti-D antibody test0s for Rhesus-D (RhD) antigen.&nbsp;The nature of the reaction between your red blood cells and the reagents determines your blood group. Remember, blood group antigens will react with their corresponding antibodies.&nbsp;Therefore, if you have A antigens on your red blood cells, they will react with anti-A antibody reagents and clump together. The reaction will appear like pellets. If the antigens on your red blood cell are different from the antibodies in the reagent, they will not react; your blood will remain fluid.If your blood reacts to anti-A and anti-B antibody reagents, it means you have blood group AB. Individuals with blood group O do not have antigens on their red blood cells, so their blood does not react with anti-A and anti-B antibodies.&nbsp;<h2 style="margin-left:0cm;">Conclusion</h2>Knowing your blood group is important for safe blood transfusion and pregnancy. It helps you to avoid or prevent severe complications that may affect individuals receiving blood transfusion or newborns. It is also important during emergencies as it will ensure timely treatment. Your knowledge could help you determine your susceptibility to certain diseases and your ancestry. Check your blood group today.

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The Prevalence of Anaemia in Africa

Does Your Blood Group Really Matter?